成果報告書詳細
管理番号20110000001061
タイトル*平成22年度中間年報 異分野融合型次世代デバイス製造技術開発プロジェクト
公開日2011/10/12
報告書年度2010 - 2010
委託先名技術研究組合BEANS研究所 国立大学法人東京大学 国立大学法人九州大学
プロジェクト番号P09008
部署名機械システム部
和文要約和文要約等以下本編抜粋:1. 研究開発の内容及び成果等
【1】 バイオ・有機材料融合プロセス技術の開発
(1A) バイオ・ナノ界面融合プロセス技術
2時間以上安定して機能する脂質二重膜の形成プロセス開発について、24時間以上安定な膜形成を達成した。これを証明するためにナノポアタンパク質であるαヘモリシンと蛍光分子のカルセインを用いた蛍光退色評価にて検証を実施した。脂質二重膜にたんぱく質を導入する技術の確立を目指し、立体構造を正しく構成させるプロセスを確立した。生体適合性界面を有する材料の開発については、ポリエチレングリコールをゲル中に加えることで、マウス耳に埋め込んだ際の炎症が抑制されることがわかった。さらに微細構造表面を有するハイドロゲルも炎症反応を抑制する可能性があるとわかった。微生物の高効率多段階反応能を最大限利用するために、微生物を多孔質担体に固定する技術を開発し、その効果を環境・エネルギー分野で注目を集めている微生物燃料電池により評価した。
英文要約Titel: Hetero-functional Integrated Device Technology Development Project (BEANS) (FY2009-FY2012) FY2010 Annual Report
We have developed the following basic technologies on hetero-functional integrated device technology. Regarding the research on process technology for bio-nano interface formation, we developed stable process for lipid bilayer for more than 24 hours and verified its function by signal attenuation of fluorescent marker. We found that hydrogel with polyethyleneglycol and with microstructure surfaces were also thought to prevent immuno-reaction in body. Regarding the research on process technology for higher-order biostructure formation, we established the method to place a sustained-release hydrogel into mouse ears. We showed that the formation of bile canaliculi was controllable by using micro structured collagen gel. Regarding the research on process technology for organic-nano interface formation, we developed high-density nano-pillar arrays by the vacuum evaporation. We also achieved the energy efficiency 4.1% by controlling the size of the nano grain of ClAlPc, and developed the organic film etching by the neutral beam irradiation of the molecular nitrogen. Regarding the research on process technology for higher-order organic structure formation, we developed nano-structure formation by block-co-polymers and synthesis technology of highly soluble ~-conjugated molecules. We also developed thermoelectric device with high power factor of Bi2Te3 on anodized porous alumina and organic double layered structure. Regarding the research on 3-dimensional nanostructure formation with ultra-low-damage etching, we developed neutral beam etching with high aspect ratio (21.8), femto-second laser assist etching of quartz substrate with a burial horizontal nanochannel of 7000 or more, and bio-assay devices which can trap a single bacterium. Regarding the research on bottom-up technology for heterogeneous integration of materials and functions on 3-D platform, We refined nanoparticle self assembly in trenches, realized a deep-UV-emitting diode(256 nm) on a silicon substrate, and achieved conformal deposition of Cu/CuMnOx layer on the oxidized surface of silicon trenches with an aspect ratio of over 114. Regarding the research on non-vacuum large-area deposition technology of high-quality nano/micro materials, we developed the strain gauges type pressure sensors using the Si films deposited at 700 Torr and the formation technology of Si oxide under the limited part atmosphere control. Regarding the research on continuous micro/nano-manufacturing and integration process for fiber substrates, we developed die-coating of 10m/min for functional materials, a compound reel-to-reel process system, an automatic weaving assembly machine, and prototyping a 1.2 x 3 m2 flexible sheet of touch sensors. Regarding the research on building up of knowledge database in heterogeneous technology convergence process development, we improved functionality of knowledge database system and completed more than 965 data registration since FY2008.
ダウンロード成果報告書データベース(ユーザ登録必須)から、ダウンロードしてください。

▲トップに戻る