成果報告書詳細
管理番号20130000000186
タイトル*平成24年度中間年報「がん超早期診断・治療機器の総合研究開発 超低侵襲治療機器システムの研究開発:高精度X線治療機器の研究開発 がんの超早期局在診断に対応した高精度X線治療システム 」
公開日2014/1/25
報告書年度2012 - 2012
委託先名国立大学法人北海道大学 国立大学法人京都大学 独立行政法人国立がん研究センター東病院 株式会社アキュセラ 株式会社日立製作所
プロジェクト番号P10003
部署名バイオテクノロジー・医療技術部
和文要約
英文要約Title:Comprehensive Research and Development of Medical Equipment for Extremely Early Detection and Treatment of Cancer / Research and Development of Super-Minimally Invasive Treatment System : Research and Development of Highly Precise X-ray Treatment Equipment / High Precision X-ray Treatment System compatible with Extremely Early Detection of Cancer (FY2010-FY2012)FY2012 Annual Report
1) It was verified that the accelerator could achieve the target specifications. The dose leakage of the accelerator was 0.07 % of the main beam dose, which met Japanese Industrial Standards (JIS). For the high power magnetron prototype, we attempted the optimization of the coaxial cavity resonator which suppressed the higher order mode, of the cathode position, and of the position of the higher order mode absorber shape, and then the expected measurement value of peak RF output 2.0 MW at duty cycle 0.0009 was obtained.
2) Prototype software including multi-gating function was developed for system integration. The real-time tumor-tracking system that utilized the hybrid-FPDs was constructed in test site. Communication function to a treatment console and a DICOM server was validated. By mounting the X-ray head including the accelerator, the electron gun, and the magnetron, on the industrial compact 6 axis robot, with the console for system control, the prototype system was completed.
3) The framework has function for simply loading of information data of machine and beam delivery of various radiotherapy systems by use of plug-in function. The function of framework improved by feeding back opinion of many medical physicists and radiation oncologists in radiotherapy. The usefulness and accuracy of developed prototype software for 4D dose calculation have been evaluated and improved. The software interface has been modified to integrate with the framework of treatment planning system. Range specification of the dose calculation, and the DVH function of the numerical result were added to the current system. We achieved optimization of the beam selection by giving the minimum influence to the surrounding organs and selected appropriate beam strength as a treatment plan function. For evaluation of the dose calculation software, the planning for the rind radiation therapy was performed using the conventional treatment planning system.
4)The algorithm of multi-gating function was developed and implemented to the software. A performance test was conducted by a film irradiation experiment. Position of a compact X-ray irradiation system was able to be controlled by RTRT software. As for the high energy treatment X-ray monitoring, we developed two prototyping systems that included a fiber scintillator monitor and a multi-gas chamber monitor. We now expect to create the excellent 200PPS high-speed detection system and X-ray detection linearity.
Treatment record verification function of the radiation treatment plan verifying system was tested with the server of the robotic linac.
5) We integrated all components described in the items 1) to 4), and built the integrated system. We confirmed this system was operated satisfactorily in case of a stereotactic radiation model and a multi-gating radiation model.
ダウンロード成果報告書データベース(ユーザ登録必須)から、ダウンロードしてください。

▲トップに戻る