成果報告書詳細
管理番号20130000000294
タイトル*平成24年度中間年報 環境・医療分野の国際研究開発・実証プロジェクト フランスにおける国際共同研究開発・実証事業 ヒト化動物を用いた次世代型がん領域創薬支援システムの研究開発・実証」(インビボサイエンス株式会社)
公開日2014/8/20
報告書年度2012 - 2012
委託先名インビボサイエンス株式会社
プロジェクト番号P11017
部署名バイオテクノロジー・医療技術部
和文要約
英文要約Title: International Research and Development, and Demonstration Projects in Environmental and Medical Technologies. Research & Development for generating new system of anti-cancer drug discovery with humanized experimental animals (FY2012 - FY2013) FY2012 Annual Report

There is no appropriate pre-clinical study for discovery of anti-caner drug. Therefore we have attempted to generate new system for anti-cancer drug discovery with humanized experimental animals. The aim of this project is to develop next generation humanized mouse as well as contract research service with it.
In-Vivo Science Inc. has played two critical roles in this project. First, developing procedures for effective production and genotyping of humanized experimental animals. It is obviously important to construct high-through put test of genotyping for genetically modified mice strains. Otherwise effective production of mice is impossible from commercial point of view. We successfully establish the test system with PCR based method.
Second, the project is supposed to be performed with French company, Oncodesign. Oncodesign has a role in conducting demonstration research using clinical materials. In-Vivo Science Inc. has responsibility to supply genetically modified mice to Oncodesign as well as technical skill transfer, To do so, we visited the headquarter of Oncodesign in Dijon, France and had a meeting with researchers of the company.
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