成果報告書詳細
管理番号20140000000178
タイトル*平成25年度中間年報 「環境・医療分野の国際研究開発・実証プロジェクト 先進的医療機器システムの国際研究開発及び実証 現地国事情に適した高品位透析治療を達成する透析水清浄化システムの研究開発・実証」
公開日2014/8/8
報告書年度2013 - 2013
委託先名東レ株式会社 東レ・メディカル株式会社 学校法人東京女子医科大学
プロジェクト番号P11011
部署名バイオテクノロジー・医療技術部
和文要約
英文要約Title: International Research and Development and Demonstration Project of Environmental and Medical Field/ International Research and Development and Demonstration of Advanced Medical System/ Research and Development of Water Purification System for dialysate to Achieve High Quality Dialysis Treatment according to the affairs of each area (FY2012-FY2014)/ FY2013 Annual Report

Research and development to optimized dialysis system for the affairs of each area contributes to develop quality of dialysis treatment and accelerate expansion of domestic medical industry in Asian countries. Our target is to demonstrate following three concepts. 1) To offer the water treatment system that is adequate to raw water environment in China and to supply super pure water for dialysate, 2) To Offer a high quality dialysis treatment by the combination of the high flux dialyzer and intermittent hemodialysis (I-HD). 3) Improve the safety and labor-saving dialysis treatment by introducing dialysis machine with navigation and automation function. To demonstrate these concepts, we made effort to develop Endotoxin Retentive Filter that has high durability and high flux dialyzer. We achieved the following results. a) We obtained hollow fiber that has low cut-off molecular weight by regulating spinning condition. We considered that this hollow fiber has high endotoxin retentive performance. b) We found that Flux and separation performance was improved by changing pore shape from circle to ellipse. The reasons were that increasing rate of holes area and reducing a minor axis. Furthermore we found that this hollow fiber had high endotoxin retentive performance.
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