成果報告書詳細
管理番号20160000000587
タイトル*平成27年度中間年報 次世代ロボット中核技術開発 革新的ロボット要素技術分野 人検知ロボットのための嗅覚受容体を用いた匂いセンサの開発
公開日2016/9/7
報告書年度2015 - 2015
委託先名国立大学法人東京大学 住友化学株式会社  公益財団法人神奈川科学技術アカデミー
プロジェクト番号P15009
部署名ロボット・AI部
和文要約
英文要約Strategic Advancement of Multi-Purpose Ultra-Human Robot and Artificial Intelligence Technologies
Future robot technology
Development of Odor Sensor Using Olfactory Receptors for Human Searching
FY2015 Annual Report (FY2015-FY2016)
With the aim of producing a human searching sensor, we address the development of a highly sensitive and selective odorant sensor using olfactory receptors from insects, especially sensitive to human odors. The sensor is expected to play a big role for robot-assisted rescue in the future. This project is carried out by three institutes, Sumitomo Chemical Company, Kanagawa Academy of Science and Technology (KAST), and The University of Tokyo. Sumitomo Chemical Company works on launching expression systems of insects' olfactory receptors and purification methods of those receptors. KAST and The University of Tokyo develop the device for applying the purified receptors to an odorant sensor. Each group activity in fiscal year 2015 is summarized below.
The group from Sumitomo Chemical Company develops the expression and purification system of olfactory receptors. The aim is to produce the olfactory receptor for the sensor device, which is able to detect human odors with high specificity and sensitivity. The group compared sensitivity of olfactory receptors derived from several insects by using cell line assay, and identified the highly sensitive olfactory receptor. Various cell lines derived from mammalian and insect have been screened for reproducible production of the olfactory receptor. Affinity tag-fused gene of the olfactory receptor has been also constructed for affinity purification.
The group from KAST develops technology to install olfactory receptors in the sensor chip. The main subjects are the integration of olfactory receptors on the artificial lipid bilayer and the development of an electrical device for capturing vaporized odors and detecting the ionic current signals from the olfactory receptors. So far, KAST group had succeeded in integrating the olfactory receptors on artificial lipid bilayers, and detected human odor molecules in liquid phase. KAST group made use of a hydrogel to capture the vaporized odors. The group is currently refining the device for the stable sensing system, compatible with an efficient capture of vaporized odor on hydrogels.
The group from The University of Tokyo designs and constructs the chassis to mount the sensor chips. The chassis includes the signal conversion system, which senses and amplifies the electrical signals from the sensor chip, and output to external equipment. The first prototype of the chassis was constructed. By a close cooperation with KAST, the group has been testing the prototype, and is now reconstructing the second prototyping chassis.
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