TKG Therapeutics, Inc.

Program name

Deep-Tech Startups Support Program

Research theme

R&D of a new immersive solid-phase synthesis method

Business Plan

We are advancing the commercialization of an immersion solid-phase synthesis method known as the 'jabot-zuke' method. This synthesis method is anticipated to enable the production of nucleic acid materials that are capable of mass production, cost-effective, and have a reduced environmental impact. By commercializing this project, we aim to contribute to the expansion of the nucleic acid materials market, including nucleic acid pharmaceuticals.

Research Outline

We are going to create a prototype of an automated synthesizer utilizing the immersion solid-phase synthesis method, aiming to achieve the following Proof of Concept (PoC) goals: 1. Synthesis on a milligram scale using the prototype machine 2. Synthesis with less than 50% of the reaction reagent amount compared to conventional solid-phase synthesis methods 3. Synthesis of our company's proprietary new functional nucleic acids.

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